1. Supervised clinical training is provided in cytotoxic drug treatment and radiation therapy.

2. Navebine is a new semi-synthetic cytotoxic drug. Distinctive anticancer activity was observed in the treatment of 32 patients with non-small cell lung cancer.

3. Patients were excluded if they had taken ulcer healing agents, antibiotics, or cytotoxic drugs within one week of endoscopy.

4. Growing awareness of the similarities between "primary" amyloidosis and that associated with myelomatosis led to the trial of cytotoxic drug such as melphalan in the former condition(19)(20).

5. Pathological change is chronic and continual advancement, patients can emerge renal inadequacy, uraemia. excitatory autacoid and cytotoxic drug have bad curative effect and major adverse reaction.