1. Disopyramide, procainamide, and quinidine are considered third-line agents in this situation.

2. Aim To investigate the pharmacological effect of procainamide on transmural ventricular repolarization.

3. The clinician may consider disopyramide, procainamide, or quinidine on an individual basis.

4. The latter is the basis of a challenge diagnostic test usually using ajmaline or procainamide.

5. Methods Compared the effect and safety of amiodarone, matrine and procainamide on ventricular arrhythmias in patients with coronary heart disease(CHD) by Holter and 12 leads electrocardiogram.